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HPGDS inhibitor 1
CAS No. 1033836-12-2
HPGDS inhibitor 1 ( H-PGDS Inhibitor I )
Catalog No. M10167 CAS No. 1033836-12-2
A potent, selective, oral hematopoietic prostaglandin D synthase (HPGDS) inhibitor with enzyme IC50 of 0.6 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 116 | In Stock |
|
| 5MG | 185 | In Stock |
|
| 10MG | 331 | In Stock |
|
| 25MG | 556 | In Stock |
|
| 50MG | 795 | In Stock |
|
| 100MG | 1071 | In Stock |
|
| 500MG | 2178 | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameHPGDS inhibitor 1
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective, oral hematopoietic prostaglandin D synthase (HPGDS) inhibitor with enzyme IC50 of 0.6 nM.
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DescriptionA potent, selective, oral hematopoietic prostaglandin D synthase (HPGDS) inhibitor with enzyme IC50 of 0.6 nM; does not inhibit human L-PGDS, mPGES, COX-1, COX-2, or 5 LOX (IC50>10 uM); reduces the antigen-induced response in vivo.
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SynonymsH-PGDS Inhibitor I
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PathwayImmunology/Inflammation
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TargetPGE synthase
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RecptorhPGDS
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number1033836-12-2
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Formula Weight381.37
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Molecular FormulaC19H19F4N3O
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(C1=CC=C(C2=CC=CC(F)=C2)N=C1)NC3CCN(CC(F)(F)F)CC3
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Chemical Name3-Pyridinecarboxamide, 6-(3-fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)-4-piperidinyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Carron CP, et al. ACS Med Chem Lett. 2010 Feb 2;1(2):59-63.
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